Great for Cystic Fibrosis

Best Electrolytes for Cystic Fibrosis

4.6 from 1086 reviews

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Sweat in cystic fibrosis runs three to five times saltier than normal, and because blood sodium does not climb as it goes, thirst never shows up to flag it. Saltivate is 800mg of sodium per serving with zero sugar. Your CF team sets how much salt you need.

30-day money-back guarantee. Free shipping over $50. Pay with your HSA/FSA card. Reviewed by the Saltivate team.

  • 800mg sodiumper serving
  • Zero sugarno stevia, Reb M
  • HSA/FSApay by card, no letter
  • Made in USAImported ingredients, NSF GMP Certified facility. Third-party tested.

Salt leaves faster in CF

In cystic fibrosis the CFTR channel does not reclaim chloride from sweat as it moves up the duct, so sodium stays with it and both end up on the skin instead of back in the body. Sweat in CF runs three to five times saltier than normal, which is why skin can taste salty and why salt crystals sometimes show up after a hot day.

Thirst does not keep pace. Salt and water leave together, so blood sodium does not rise the way it does in ordinary dehydration and the signal to drink never arrives. Losses build quietly through hot weather, exercise, fevers, and infections.

There is no standard replacement dose. Needs move with sweat chloride level, sweat rate, climate, activity, symptoms, and whether you are on a CFTR modulator. Your CF team sets the number.

Signs of salt depletion

  • Fatigue and lethargy
  • Headaches
  • Trouble concentrating
  • Dizziness or light-headedness
  • Nausea or vomiting
  • Muscle cramps or weakness
  • Dark, strong-smelling urine
  • Appetite and thirst dropping off
  • Salt crystals on the skin

What actually replaces the salt

Sodium is the electrolyte that holds fluid in the body, so replacing it matters more than drinking more water. Water on its own dilutes the sodium that is left.

Sports drinks were never designed around CF losses, and their sodium shows it. Per liter, Gatorade Endurance powder carries about 830mg, regular Gatorade about 510mg, Powerade Zero about 420mg, and Prime about 30mg. CF clinic handouts routinely tell people to stir an eighth of a teaspoon of table salt into a bottle of sports drink to close the gap. For scale, a teaspoon of table salt holds roughly 2,000mg of sodium and a standard salt tablet holds 240mg.

One serving of Saltivate is 800mg of sodium from sodium chloride, plus 240mg potassium and 60mg magnesium, with zero sugar. Raw Unflavored is the plain version, roughly 2g of salt and no sweetener at all, so it stirs into water, juice, or milk without turning every glass of the day into a sweet drink.

CFTR modulators change the picture. Elexacaftor, tezacaftor, and ivacaftor together roughly halve sweat chloride, and a 2025 study in the Journal of Cystic Fibrosis reported that the combination corrects salt wasting, with the authors noting that salt replacement warrants a fresh look in people on that therapy. Whether you still need extra salt, and how much, is a question for your CF team.

Why Saltivate suits a CF salt routine

Saltivate exists because most electrolyte drinks underdose the one mineral you lose most in sweat. In cystic fibrosis the losses start larger, so that gap is wider again.

Raw Unflavored carries the sodium with no sweetener at all, so it can go into water, juice, milk, or a smoothie without adding sugar to every drink. The flavored mixes use OnoSweet, a Reb M made by fermenting rice rather than taken from the stevia leaf, so there is no stevia aftertaste to fight when someone has to drink it daily.

  • 800mg sodium per serving from sodium chloride, plus 240mg potassium and 60mg magnesium
  • Zero sugar, and zero calories in Raw Unflavored, so a daily salt habit does not come with a daily sugar habit
  • Raw Unflavored is plain with no sweetener at all, so it mixes into water, juice, or milk
  • Pay with an HSA or FSA card at checkout, no letter needed

Try it. Sweat on it. Decide later.

Every order carries a 30-day money-back guarantee. If it is not for you, email us and we refund you in full. You do not even ship anything back.

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What customers say

Rated 4.53 out of 5 from 34 reviews

★★★★★
Easy to drink, Tastes like nothing!
Easy to drink, Tastes like nothing!

Carl D. · Verified buyer

★★★★★
I wasn't sure what to expect, so I was so
I wasn't sure what to expect, so I was so pleased that not only was the unflavored very satisfying in it's taste, but the flavored samples really caught me by surprise. Every electrolyte flavor I tried in the past was pretty awful, flavor so intense...

Barb · Verified buyer

★★★★★
My results on using this product
I have been running for 15 years and stopped drinking sport drinks and replace it with a grape cranberry 100% juice mixed with water however I found that in the Texas heat i would feel slightly dizzy and light headed after I stopped running during...

Jeff F. · Verified buyer

Read all 34 reviews

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Common questions

Why do people with cystic fibrosis lose so much salt?

The CFTR channel normally reclaims chloride from sweat before it reaches the skin, and sodium follows it back in. In CF that reabsorption fails, so both minerals leave with the sweat. Sweat in CF runs three to five times saltier than normal.

How much extra salt does someone with CF need?

There is no standard replacement dose. Needs move with sweat chloride level, sweat rate, climate, activity, symptoms, and whether you are on a CFTR modulator. A sweat test can help your CF dietitian set it. Once you have a number, Saltivate's 800mg of sodium per serving makes it easier to reach without measuring salt by the spoonful.

Why does thirst not warn you?

In ordinary dehydration, blood sodium rises as water is lost and that triggers thirst. In CF the salt leaves alongside the water, so blood sodium stays flat and thirst is never prompted. Salt depletion can build without the usual warning, which is why CF care teams talk about drinking to a plan rather than to thirst.

Do CFTR modulators change how much salt is needed?

They appear to. Elexacaftor, tezacaftor, and ivacaftor roughly halve sweat chloride, and a 2025 study in the Journal of Cystic Fibrosis found the combination corrects salt wasting, with higher plasma sodium and more urinary sodium excretion. The authors flagged that salt replacement should be reconsidered on that therapy. Ask your CF team where you stand before changing anything.

How does it compare to a sports drink?

Per liter, Gatorade Endurance powder carries about 830mg of sodium, regular Gatorade about 510mg, Powerade Zero about 420mg, and Prime about 30mg. One serving of Saltivate is 800mg with zero sugar, and Raw Unflavored has no sweetener at all, so you decide how much water it goes into.

Can children with cystic fibrosis use it?

Salt for a child with CF is set by the CF team, and infants are usually given sodium directly rather than through a drink. Ask your CF dietitian before adding any electrolyte mix to a child's routine, and let them set the amount.

What about hot weather, exercise, and fevers?

Those are the conditions CF clinics flag, because more sweat means more salt gone. Handouts commonly suggest adding an eighth of a teaspoon of table salt to a sports drink during heavy sweat. Saltivate covers that in one serving, with no sugar attached.

Why unflavored rather than a flavored mix?

Raw Unflavored has no sweetener at all, so it can go into water, juice, milk, or a smoothie without changing what the drink is. Its roughly 2g of salt lightly seasons whatever it goes into. The flavored options in Orange, Mango Pineapple, and Watermelon are sweetened with OnoSweet, a Reb M made by fermenting rice rather than taken from the stevia leaf, so there is no bitter aftertaste.

Is Saltivate HSA or FSA eligible?

Yes. You can pay with an HSA or FSA card at checkout, and no Letter of Medical Necessity is needed.

Salt without the sugar

Raw Unflavored is 800mg of sodium a serving with no sweetener, and it stirs into whatever is already in the glass. Your CF team sets how much you need.

Shop Raw Unflavored

Sources

Cited for general background only. Follow your own clinician's guidance for your sodium and fluid targets.

How we compare

How Saltivate compares

Pick the format you shop, then see how Saltivate stacks up against the brands that sell it too.

Compare what matters for sweat recovery: sodium per serving, zero sugar, and paying direct with your HSA/FSA card with no letter of medical necessity.

Flavor
Format
SaltivateBPN ElectrolytesCarnivoreCureDr. Berg's Electrolyte PowderGatoradeGHOST HydrationGood IntentionsHRDWRKHydrate ProJust Ingredients ElectrolytesLiquid I.V.Promix Electrolyte Drink MixRe-LyteSanta Cruz PaleoSkratchTreviUltima
Serving size1 stick (3.15g)1 scoop (5.6g)1 scoop (~3g)1 scoop (8.3g)1 scoop (6g)1 powder stick (35g)1 scoop (9g)1 scoop (2.69g)1 scoop (3g)1 scoop (4.93g)1 scoop (5.7g)1 scoop1 scoop (5.18g)1 scoop (7g)1 scoop (5.42g)1 packet (22g)1 stick (4.8g)1 stick/scoop
Sodium800mg (from salt)500mg (from himalayan pink salt, citrate)500mg (from citrate)240mg (from salt)40mg (from pink himalayan salt)230mg (from salt, citrate)150mg (from citrate, himalayan pink salt)200mg (from salt)650mg (from citrate, bicarbonate, chloride)1000mg (from salt)100mg (from salt)510mg (from salt, citrate)1000mg (from salt (himalayan pink))810mg (from salt)800mg (from salt)400mg (from citrate)230mg (from pink himalayan salt)55mg (from salt)
Potassium240mg (from citrate)200mg (from chloride)300mg (from citrate, bicarbonate)310mg (from coconut water)1000mg (from citrate)70mg (from phosphate)375mg (from citrate)200mg (from chloride)300mg (from bicarbonate)200mg (from chloride)300mg (from citrate)390mg (from citrate)200mg (from chloride)400mg (from citrate)300mg (from chloride)49mg (from citrate)250mg (from phosphate, citrate)250mg (from phosphate)
Magnesium60mg (from malate)25mg (from bisglycinate chelate)40mg (from oxide, citrate)0mg120mg (from citrate)0mg83mg (from citrate)42mg (from malate)150mg (from glycinate, citrate)60mg (from glycinate)50mg (from citrate)0mg60mg (from malate)50mg (from glycinate, malate)60mg (from glycinate)48mg (from carbonate)100mg (from citrate)100mg (from citrate)
Sugar0g0g0g0g0g32g0g0g0g0g0g11g0g0g0g19g0g0g
SweetenerNoneStevia (steviol glycosides)SteviaStevia, monk fruitSteviaSugar, dextroseSucraloseSteviaSucralose, natural steviaSteviaStevia, monk fruitCane sugar, dextrose, steviaMonk fruit (lightly sweetened versions)SteviaOrganic steviaCane sugar, dextroseSucralose, steviaStevia
Artificial ingredientsNoneArtificial flavors, dyes (Yellow 5, Red 40)Sucralose, Artificial flavors, dyes (Red 40, Blue 1)Sucralose, Artificial flavorsSucralose
Pay with HSA/FSA cardYesNoNoYesNoNoNoNoNoNoNoNoNoNoNoNoNoNo
Made inUSAUnknownUSAUSAUSAUSAUSAUnknownUnknownUSAUSAUSAUSAUSAUSAUSAUSAUSA
Servings per unit45 sticks50 (jar)90 (jar)28 (jar)50 (jar)30 sticks40 (jar)100 (jar)100 (jar)45 (jar)30 (jar)30 (jar)30 (jar)60 (jar)30 (tub)20 servings45 (jar)20 sticks
Price per serving$0.89$0.90$0.46$1.37$0.97$0.90$0.82$0.22$0.30$0.78$0.83$1.39$1.40$0.77$1.00$1.20$0.78$1.05
Price per 1,000mg key electrolytes i$0.80$1.24$0.54$2.49$0.83$3.00$1.34$0.49$0.27$0.61$1.84$1.54$1.11$0.61$0.86$2.41$1.34$2.59
Ways to save moreBuy 3 Get 1 -25%HSA/FSA -30%Varies by brandVaries by brandVaries by brandVaries by brandVaries by brandVaries by brandVaries by brandVaries by brandVaries by brandVaries by brandVaries by brandVaries by brandVaries by brandVaries by brandVaries by brandVaries by brandVaries by brand

Per serving, from each brand's published label. Values can vary by flavor and change over time.